Review Articles

2015

1. Chanmee T, Ontong P, *Itano N. Hyaluronan: A modulator of the tumor microenvironment. Cancer Lett. S0304-3835(16)30099-4. doi: 10.1016/j.canlet.2016.02.031. 2015.
2. Chanmee T, Ontong P, Kimata K, *Itano N. Key roles of hyaluronan and its CD44 receptor in the stemness and survival of cancer stem cells. Front Oncol. 10;5:180. doi: 10.3389/fonc.2015.00180. eCollection 2015.

2014

3. Chanmee, T., Ontong, P., Konno, K., and *Itano N. Tumor-associated macrophages as major players in the tumor microenvironment. Cancers 6(3):1670-1690. 2014.

2011

4. Iijima, J., Konno, K., and *Itano, N. Inflammatory alterations of the extracellular matrix in the tumor microenvironment. Cancers 3: 3189-3205, 2011.

2008

5. *Itano, N., Zhuo, L., and Kimata, K. Impact of the hyaluronan-rich tumor microenvironment on cancer initiation and progression. Cancer Sci. 99:1720-1725. 2008.
6. Itano, N., and *Kimata, K. Altered hyaluronan biosynthesis in cancer progression. Semin. Cancer Biol. 18:268-274. 2008.
7. *Itano, N. Simple primary structure, complex turnover regulation and multiple roles of hyaluronan. J. Biochem. 144:131-137. 2008.
8. *Itano, N., Hyaluronan synthase assay. In Experimental Glycoscience (Eds. N. Taniguchi, A., Suzuki, Y. Ito, H. Narimatsu, T. Kawasaki, S. Hase) Springer, 2008.
9. *Itano, N., Conditional transgenic mouse of hyaluronan synthase: a potential model of advanced beast cancer. In Experimental Glycoscience (Eds. N. Taniguchi, A., Suzuki, Y. Ito, H. Narimatsu, T. Kawasaki, S. Hase) Springer, 2008.

2005

10. *Itano, N., Kakizaki, I., Mita, S., Endo, M., Takagaki, K., and Kimata, K. A mechanism for 4-methylumbelliferone-mediated inhibition of hyaluronan biosynthesis. In Hyaluronan: Structure, metabolism, biological activities, therapeutic applications (Eds, E.A., Balazs and V.C., Hascall) Matrix Biology Institute, 2005.

2004

11. *Itano, N. Abnormal hyaluronan synthesis and cancer progression. Trends Glycosci. Glycotech. 16:199-210, 2004
12. Zhuo, L., Shen, L., Nonogaki, T., Wu, J., Itano, N., Watanabe, H., and *Kimata, K. Biological function of hyaluronan-SHAP covalent complex. In Chemistry and Biology of Hyaluronan. (Eds, H. G. Garg & C. A. Hales), Marcel Dekker, Netherland, 2004

2002

13. *Itano, N., and Kimata, K. Mammalian hyaluronan synthases. IUBMB Life. 54:195-199, 2002

2001

14. *Itano, N. Hyaluronan biosynthesis: A multifaceted process. Connective Tissue 33:221-226, 2001
15. Sawai, T., Itano, N., Yoshida, M.and *Kimata, K. Regulation of hyaluronan synthase : negative effects on the hyaluronan synthetic activity of the mutated HAS protein that has no enzymatic activity. In International Congress Series New Developments in Glycomedicine. M. Endo, S. Harata, Y. Saito, A. Munakata, M. Sasaki, and S. Tsuchida (eds) pp183-187 Elsevier Science. 2001

1998

16. Itano, N., and *Kamata, K. Hyaluronan synthase: New directions for hyaluronan research. Trends Glycosci. Glycotech. 10:23-38, 1998
    

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